Samira Kiani

Samira Kiani

Company: University of Pittsburgh

Job title: Associate Professor of Pathology and Bioengineering


Samira Kiani is an associate professor of pathology and bioengineering at University of Pittsburgh and cofounder and CEO of GenexGen, Inc. Her work combines synthetic biology and epigenetic engineering to modulate the immune system and address safety issues associated with the gene therapies. She started working in the area of genetic engineering in 2010 at Massachusetts Institute of Technology and opened her own research lab at Arizona State University in 2016. She is the recipient of a number of grants from National Institute of Health and DARPA and has served as a Lechner Leadership Fellow at the AAAS’s Center for Public Engagement with Science and Technology. Her work increasingly extends beyond the laboratory. She is an advocate for transformation of innovation processes with the focus on enriching humans behind innovation and addressing social and ethical implications of novel biotechnological discoveries.


Understanding and Modulating the Innate Immune Response to Address the Immunogenicity of AAVs 9:45 am

AAV injection causes systemic innate immune response marked by cytokine response and Myd88 over-expression Modulating Myd88 as a key node in innate immunity impacts the adaptive immunity to AAV Engineering Myd88 regulators can be a novel tool to control AAV immunogenicity in vivoRead more

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