Workshop C – Navigating Predictability of Translational Models when Moving to First-In-Human Trials
Time: 1:00 pm
day: Preclinical Track - PM
Details:
- Approaching immunogenicity testing strategies in larger animal models such as non-human primates
- Discussing the practicalities of moving away from mice models for proof-of-concept studies
- Evaluating the use of in vitro human cell models and organoids to predict immune responses
- Assessing the relevance of preclinical data to inhuman-trials
- Highlighting the translational challenges relating to immune responses to the transgene specifically
