9:30AM Strategic Approaches to Implement Repeat Dosing
Time: 9:30 am
day: Conference Day 1
Details:
• Develop standardized, sensitive assays to interpret TAb and NAb responses across AAV serotypes, leveraging lessons from companion diagnostics for consistent therapeutic class interpretation
• Identify clinically impactful anti-AAV titers, assess the relevance of systemic titers for local therapies, and explore dosing strategies over low-titer responses as seen with Hemegenix
• Establish bioanalytical approaches to mitigate immune responses and enable repeat AAV dosing, ensuring diagnostics align across different products in the same class
