Company: Sangamo Therapeutics
Job title: Senior Director Bioanlytical Sciences
Dr. Yanmei Lu is currently the Senior Director of Biomarker and BioAnalytical Sciences at Sangamo Therapeutics, Inc. Her group responsibilities include developing and performing molecular biology, biochemical, immunochemical and cell-based assays to support nonclinical and clinical studies as well as designing and implementing translation biomarker strategies for Gene Therapy, Cell Therapy and Genome Editing programs.Prior to joining Sangamo, Dr. Lu acquired extensive experience at Genentech in developing PK, biomarker, immunogenicity and functional assays for antibody screening, candidate selection and in vivo studies to evaluate PK/PD, efficacy and safety of large molecule therapeutics in disease areas of Immunology, Oncology, Neurosciences and Ophthalmology. Dr. Lu holds a PhD in Biochemistry and Molecular Biology from University of South Florida and has published over 40 peer-reviewed articles.
Live Q&A – Ask the speakers your questions 1:20 pm
day: Day One
Immunogenicity Assay Challenges and Strategies for Gene Therapy 12:00 pm
• Evaluate most appropriate methods for developing and validating assays used to detect gene therapy immunogenicity • Developing assays to better understand gene therapy immunogenicity • What challenges must be overcome to develop high performing assaysRead more
day: Day One