KP Kruti Patel

Company: Solid Biosciences

Job title: Associate Director

Seminars:

Panel Discussion: Differences in Local & Systemic Immunogenicity Considerations 3:00 pm

Examining the differential immune landscapes in local and systemic gene therapies  Discussing pre-existing immunity to the transgene product in both local and systemic approaches The future role of machine learning for predicting immunogenicity risks based on preclinical and clinical data to advance personalized medicine approachesRead more

day: Conference Day Two

Assessing Pre-Existing Antibodies in DMD Patients 2:00 pm

Analysing the dose-dependent relationship between AAV titer, complement activation, and potential off-target effects in systemic gene therapy Exploring the rationale and potential limitations of co-administration of complement inhibitors with systemic AAV vectors  Discussing the potential of next-gen vectors with reduced complement recognition for improved systemic deliveryRead more

day: Conference Day One