Considerations for Improved Measurement of the AAV-Specific Immune Responses

Time: 1:20 pm
day: Day Two

Details:

• How to determine the AAV NAb titers in samples with matrix effect
• Examine if its sufficient to only use IFNg ELISPOT to monitor T-cell activation in AAV-based gene therapy trials
• Discuss whether animal models can predict immunogenicity of AAV in humans

Speakers: