Approach for Modeling and Species-Translation of Biodistribution, Transduction and Efficacy of AAV-based Gene Therapies
Time: 10:00 am
day: Day Two
Details:
- Data-driven identification of Dose, Serotype, Construct, Target tissue and Species dependencies of AAV treatment response
- Role of modeling in preclinical evaluation of AAV gene therapies – optimizing biodistribution study designs
- Use QSP modeling frameworks for species translation and minimum effective dose determination
